DNA origami assembled spheroid for evalu-ating cytotoxicity and infltration of chime-ricantigen receptor macrophage (CAR-M)
This study, published on the preprint platform“bioRxiv”,is based on our assembled 3D ovariancancer spheroid model as the technical platform toevaluate the targeting, killing, and infiltrationcapabilities of CAR-M in solid tumors. The researchprovided an effective high-throughput validationplatform fornewtarget screeningandpharmacodynamicevaluationofCAR-Mtherapies